DR1 Polyclonal Antibody | G-AB-08145

DR1 Polyclonal Antibody | G-AB-08145 | Gentaur Antibodies

Overview: This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: DR1, NC2, NC2-BETA, NC2B, NCB2

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 1810

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human DR1 (NP_001929.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q01658

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

DR1 Polyclonal Antibody DataSheet