DRG1 Polyclonal Antibody | G-AB-02441
Gentaur Antibodies
- SKU:
- G-AB-02441
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
DRG1 Polyclonal Antibody | G-AB-02441 | Gentaur Antibodies
Overview: DRG1 (developmentally regulated GTP binding protein 1) , also known as NEDD3 (neural precursor cell expressed developmentally down-regulated protein 3) , is a 367 amino acid protein that localizes to the cytoplasm and belongs to the GTP1/OBG family. Expressed at high levels in heart, kidney and skeletal muscle and at lower levels in brain, liver, placenta, lung, colon and spleen, DRG1 binds to TAL1 and TAL2 and is thought to play a role in cell proliferation and differentiation, as well as in apoptosis, suggesting a role in tumor formation and metastasis. DRG1 is subject to polyubiquitination and sumoylation, the former of which induces proteolytic degradation. The gene encoding DRG1 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Signal Transduction
Synonyms: Developmentally regulated GTP binding protein 1, Developmentally-regulated GTP-binding protein 1, DKFZp434N1827, DRG 1, DRG-1, DRG1, DRG1, NEDD 3, NEDD-3, NEDD3, Neural precursor cell expressed developmentally down regulated protein 3, Neural precursor cell expressed developmentally down-regulated protein 3
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: BC019285
Clonality: Polyclonal
Immunogen: Recombinant protein of human DRG1
Clone #:
Conjugation: Unconjugated
Swissprot: Q9Y295
Santa Cruz: sc-68319/sc-68321
Calculated MW: 41 kDa
Observed MW:
Concentration: 0.6 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: WB, ELISA
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.