DROSHA Polyclonal Antibody | G-AB-12145
Gentaur Antibodies
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Gentaur Antibodies
DROSHA Polyclonal Antibody | G-AB-12145
- SKU:
- G-AB-12145
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
DROSHA Polyclonal Antibody | G-AB-12145 | Gentaur Antibodies
Overview: This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA) , which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Synonyms: DROSHA, ETOHI2, HSA242976, RANSE3L, RN3, RNASE3L, RNASEN
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID: 29102
Accession #:
Clonality:
Immunogen: A synthetic peptide of human DROSHA (NP_037367.3) .
Clone #:
Conjugation: Unconjugated
Swissprot: Q9NRR4
Santa Cruz:
Calculated MW: 138 kDa/151 kDa/155 kDa/159 kDa
Observed MW: 180 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IF
Dilution: WB 1:500-1:2000 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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