DUSP12 Polyclonal Antibody | G-AB-05039

DUSP12 Polyclonal Antibody | G-AB-05039 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38) , which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: Dual specificity phosphatase 12, Dual specificity protein phosphatase 12, Dual specificity tyrosine phosphatase YVH1, DUS12, DUSP 1, DUSP 12, DUSP1, DUSP12, Serine/threonine specific protein phosphatase, TDSP4, YVH 1, YVH1, YVH1 protein tyrosine phosphatase (S. cerevisiae) ortholog, YVH1 protein tyrosine phosphatase ortholog

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC006286

Clonality: Polyclonal

Immunogen: Recombinant protein of human DUSP12

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UNI6

Santa Cruz: sc-69165

Calculated MW: 38 kDa

Observed MW:

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, ELISA

Dilution: WB 1:200-1:1000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

DUSP12 Polyclonal Antibody DataSheet