DUSP22 Polyclonal Antibody | G-AB-02001

DUSP22 Polyclonal Antibody | G-AB-02001 | Gentaur Antibodies

Overview: Mitogen-activated protein (MAP) kinases are a large class of proteins involved in Signal Transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.

Category Type: Polyclonal Antibody

Research Areas: Cell Biology, Signal Transduction

Synonyms: Dual specificity protein phosphatase 22, DUS22, Dusp22, JNK stimulatory phosphatase 1, JNK-stimulatory phosphatase-1, JSP 1, JSP-1, JSP1, LMW DSP2, LMW-DSP2, Low molecular weight dual specificity phosphatase 2, MAP kinase phosphatase x, Mitogen activated protein kinase phosphatase x, Mitogen-activated protein kinase phosphatase x, MKP-x, MKPX

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC016844

Clonality: Polyclonal

Immunogen: Recombinant protein of human DUSP22

Clone #:

Conjugation: Unconjugated

Swissprot: Q9NRW4

Santa Cruz: sc-47935

Calculated MW:

Observed MW:

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

DUSP22 Polyclonal Antibody DataSheet