DUSP22 Polyclonal Antibody | G-AB-11601

DUSP22 Polyclonal Antibody | G-AB-11601 | Gentaur Antibodies

Overview: Mitogen-activated protein (MAP) kinases are a large class of proteins involved in Signal Transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.

Category Type: Polyclonal Antibody

Research Areas: Cell Biology, Signal Transduction

Synonyms: DUSP22, JKAP, JSP-1, JSP1, LMW-DSP2, LMWDSP2, MKP-x, MKPX, VHX

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 56940

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human DUSP22 (NP_064570.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9NRW4

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

DUSP22 Polyclonal Antibody DataSheet