EIF4EBP1 Polyclonal Antibody | G-AB-01924

EIF4EBP1 Polyclonal Antibody | G-AB-01924 | Gentaur Antibodies

Overview: This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E) , which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism

Synonyms: 4E-BP1, 4EBP1, 4EBP1, BP 1, eIF4E binding protein 1, eIF4E-binding protein 1, Eif4ebp1, Eukaryotic translation initiation factor 4E-binding protein 1, PHAS-I, PHASI, Phosphorylated heat- and acid-stable protein regulated by insulin 1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC004459

Clonality: Polyclonal

Immunogen: Recombinant protein of human EIF4EBP1

Clone #:

Conjugation: Unconjugated

Swissprot: Q13541

Santa Cruz: sc-6024/sc-6025/sc-6936

Calculated MW: 13 kDa

Observed MW:

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

EIF4EBP1 Polyclonal Antibody DataSheet