ENG Polyclonal Antibody | G-AB-00331

ENG Polyclonal Antibody | G-AB-00331 | Gentaur Antibodies

Overview: ENG (Endoglin) is a Protein Coding gene. Diseases associated with ENG include Telangiectasia, Hereditary Hemorrhagic, Type 1 and Hereditary Hemorrhagic Telangiectasia. Among its related pathways are Angiogenesis (CST) and HIF-1-alpha transcription factor network. GO annotations related to this gene include protein homodimerization activity and glycosaminoglycan binding. An important paralog of this gene is TGFBR3. This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Immunology, Stem Cells, Cancer, Cardiovascular

Synonyms: AI528660, AI662476, CD 105, CD105, CD105 antigen, EGLN, END, Endoglin, Eng, FLJ41744, HHT1, ORW, ORW1, Osler Rendu Weber syndrome 1, RP11 228B15.2, S-endoglin, SN6

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 13805

Accession #:

Clonality: Polyclonal

Immunogen: Recombinant Mouse Endoglin protein

Clone #:

Conjugation: Unconjugated

Swissprot: Q63961

Santa Cruz:

Calculated MW: 70 kDa

Observed MW: 70 kDa

Concentration: 0.19 mg/mL

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3

Purification method: Antigen Affinity Purification

Application: WB, IHC

Dilution: WB 1:500-1:1000 IHC 1:50-1:150

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ENG Polyclonal Antibody DataSheet