EPOR Polyclonal Antibody | G-AB-02743
Gentaur Antibodies
- SKU:
- G-AB-02743
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
EPOR Polyclonal Antibody | G-AB-02743 | Gentaur Antibodies
Overview: This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Immunology, Signal Transduction, Stem Cells
Synonyms: EPO R, EPO-R, epor, EPOR, Erythropoietin receptor, Erythropoietin receptor precursor, MGC138358
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: NP_000112
Clonality: Polyclonal
Immunogen: Synthetic peptide of human EPOR
Clone #:
Conjugation: Unconjugated
Swissprot: P19235
Santa Cruz: sc-82590/sc-82593/sc-697/sc-5624/sc-695
Calculated MW:
Observed MW:
Concentration: 0.7 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: IHC, ELISA
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.