EPS15L1 Polyclonal Antibody | G-AB-11888
Gentaur Antibodies
- SKU:
- G-AB-11888
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
EPS15L1 Polyclonal Antibody | G-AB-11888 | Gentaur Antibodies
Overview: Epidermal growth factor receptor substrate 15-like 1is aproteinthat in humans is encoded by theEPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR) ; internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) By similarity. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Signal Transduction
Synonyms: EPS15L1, EPS15R
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID: 58513
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human EPS15L1 (NP_001245304.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: Q9UBC2
Santa Cruz:
Calculated MW: 66 kDa/83 kDa/94 kDa/99 kDa
Observed MW: 110 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.