ERCC2 Polyclonal Antibody | G-AB-08729

ERCC2 Polyclonal Antibody | G-AB-08729 | Gentaur Antibodies

Overview: The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: ERCC2, COFS2, EM9, TFIIH, TTD, TTD1, XPD

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 2068

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ERCC2 (NP_001124339.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P18074

Santa Cruz:

Calculated MW: 46 kDa/86 kDa

Observed MW: 80 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ERCC2 Polyclonal Antibody DataSheet