ERCC2 Polyclonal Antibody | G-AB-10753

ERCC2 Polyclonal Antibody | G-AB-10753 | Gentaur Antibodies

Overview: The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: ERCC2, COFS2, EM9, TFIIH, TTD, TTD1, XPD

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 2068

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ERCC2 (NP_001124339.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P18074

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ERCC2 Polyclonal Antibody DataSheet