F3 Polyclonal Antibody | G-AB-06983

F3 Polyclonal Antibody | G-AB-06983 | Gentaur Antibodies

Overview: This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular

Synonyms: CD142, CD142 antigen, Coagulation factor III (thromboplastin tissue factor) , Coagulation factor III, F3, FLJ17960, TF, TF, TFA, Thromboplastin, Tissue factor

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP001984

Clonality: Polyclonal

Immunogen: Synthetic peptide of human F3

Clone #:

Conjugation: Unconjugated

Swissprot: P13726

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1.3 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:40-1:250, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

F3 Polyclonal Antibody DataSheet