F7 Polyclonal Antibody | G-AB-02140

F7 Polyclonal Antibody | G-AB-02140 | Gentaur Antibodies

Overview: This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular

Synonyms: coagulation factor VII (serum prothrombin conversion accelerator) , Coagulation factor VII, Eptacog alfa, F7, FA7, Factor VII, Factor VII heavy chain, Factor VII light chain, FVII coagulation protein, OTTHUMP00000018733, OTTHUMP00000018734, Proconvertin, Serum prothrombin conversion accelerator, SPCA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC130468

Clonality: Polyclonal

Immunogen: Recombinant protein of human F7

Clone #:

Conjugation: Unconjugated

Swissprot: P08709

Santa Cruz: sc-16343/sc-16344/sc-16347

Calculated MW: 49 kDa

Observed MW:

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

F7 Polyclonal Antibody DataSheet