FGB Polyclonal Antibody | G-AB-08532

FGB Polyclonal Antibody | G-AB-08532 | Gentaur Antibodies

Overview: The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cardiovascular

Synonyms: FGB, HEL-S-78p

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 2244

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human FGB (NP_005132.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P02675

Santa Cruz:

Calculated MW: 55 kDa

Observed MW: 56 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

FGB Polyclonal Antibody DataSheet