FGR Polyclonal Antibody | G-AB-09923

FGR Polyclonal Antibody | G-AB-09923 | Gentaur Antibodies

Overview: This gene is a member of the Src family of protein tyrosine kinases (PTKs) . The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin Signal Transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: FGR, SRC2, c-fgr, c-src2, p55-Fgr, p55c-fgr, p58-Fgr, p58c-fgr

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 2268

Accession #:

Clonality:

Immunogen: A synthetic peptide of human FGR (NP_005239.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P09769

Santa Cruz:

Calculated MW: 59 kDa

Observed MW: 53 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

FGR Polyclonal Antibody DataSheet