FLNA Polyclonal Antibody | G-AB-11929

FLNA Polyclonal Antibody | G-AB-11929 | Gentaur Antibodies

Overview: The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4) , otopalatodigital syndromes (OPD1, OPD2) , frontometaphyseal dysplasia (FMD) , Melnick-Needles syndrome (MNS) , and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX) . Two transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: FLNA, ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD, filamin-A

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 2316

Accession #:

Clonality:

Immunogen: A synthetic peptide of human FLNA (NP_001104026.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P21333

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

FLNA Polyclonal Antibody DataSheet