GAD1 Polyclonal Antibody | G-AB-03476

GAD1 Polyclonal Antibody | G-AB-03476 | Gentaur Antibodies

Overview: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Immunology, Signal Transduction

Synonyms: 67 kDa glutamic acid decarboxylase, CPSQ1, DCE1, DCE1, EC 4.1.1.15, FLJ45882, GAD 67, GAD, GAD-67, GAD1, Glutamate decarboxylase 1 (brain, 67kDa) , Glutamate decarboxylase 1, Glutamate decarboxylase 1 brain 67kD, Glutamate decarboxylase 1 brain 67kDa, Glutamate decarboxylase 67 kDa isoform, Glutamate decarboxylase, brain, 67-KD, OTTHUMP00000041055, SCP

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_000808

Clonality: Polyclonal

Immunogen: Synthetic peptide of human GAD1

Clone #:

Conjugation: Unconjugated

Swissprot: Q99259

Santa Cruz: sc-7512/sc-7513/sc-5602

Calculated MW: 67 kDa

Observed MW:

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:200-1000, IHC 1:25-100, ELISA 1:1000-2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

GAD1 Polyclonal Antibody DataSheet