GCK Polyclonal Antibody | G-AB-02509

GCK Polyclonal Antibody | G-AB-02509 | Gentaur Antibodies

Overview: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM) , maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI) .

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: ATP:D-hexose 6-phosphotransferase, FGQTL3, GCK, GK, GLK, Glucokinase, Hexokinase D pancreatic isozyme, Hexokinase type IV, Hexokinase-4, Hexokinase-D, HHF3, HK IV, HK4, HKIV, HXK4, HXKP, LGLK, MODY2

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC001890

Clonality: Polyclonal

Immunogen: Recombinant protein of human GCK

Clone #:

Conjugation: Unconjugated

Swissprot: P35557

Santa Cruz: sc-1980/sc-1979/sc-55496/sc-7908/sc-130765

Calculated MW:

Observed MW:

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:100-1:300

Storage: Store at -20°C. Avoid freeze / thaw cycles.

GCK Polyclonal Antibody DataSheet