GLUD1 Polyclonal Antibody | G-AB-11774
Gentaur Antibodies
- SKU:
- G-AB-11774
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
GLUD1 Polyclonal Antibody | G-AB-11774 | Gentaur Antibodies
Overview: This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Metabolism, Signal Transduction
Synonyms: GLUD1, GDH, GDH1, GLUD
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 2746
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human GLUD1 (NP_005262.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: P00367
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC, IF
Dilution: IHC 1:100-1:200 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.