GNRHR Polyclonal Antibody | G-AB-02776

GNRHR Polyclonal Antibody | G-AB-02776 | Gentaur Antibodies

Overview: This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH) . Defects in this gene are a cause of hypogonadotropic hypogonadism (HH) . Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience

Synonyms: GnRH receptor, GnRH-R, GNRHR, GNRHR, GNRHR1, Gonadotropin releasing hormone receptor, gonadotropin-releasing hormone (type 1) receptor 1, Gonadotropin-releasing hormone receptor, GRHR, HH7, leutinizing-releasing hormone receptor, lh-rh, LHRHR, LRHR, luliberin receptor, luteinizing hormone releasing hormone receptor, type I GnRH receptor

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_000397

Clonality: Polyclonal

Immunogen: Synthetic peptide of human GNRHR

Clone #:

Conjugation: Unconjugated

Swissprot: P30968

Santa Cruz: sc-8681/sc-8682/sc-13944

Calculated MW: 28 kDa

Observed MW:

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:2000-1:5000, IHC 1:150-1:500

Storage: Store at -20°C. Avoid freeze / thaw cycles.

GNRHR Polyclonal Antibody DataSheet