GPR124 Polyclonal Antibody | G-AB-01704

GPR124 Polyclonal Antibody | G-AB-01704 | Gentaur Antibodies

Overview: Tumor endothelial markers (TEMs) are abundantly expressed in the blood vessels of human solid tumors during angiogenesis and neoangiogensis. These include TEM1 (endosialin) , TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1) . TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: DKFZp434C211, DKFZp434J0911, FLJ14390, G protein coupled receptor 124, G-protein coupled receptor 124, GP124, GPR 124, Gpr124, KIAA1531, TEM 5, TEM5, Tumor endothelial marker 5, Tumor endothelial marker 5 precursor

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_116166

Clonality: Polyclonal

Immunogen: Synthetic peptide of human GPR124

Clone #:

Conjugation: Unconjugated

Swissprot: Q96PE1

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

GPR124 Polyclonal Antibody DataSheet