GRM1 Polyclonal Antibody | G-AB-07480

GRM1 Polyclonal Antibody | G-AB-07480 | Gentaur Antibodies

Overview: This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience

Synonyms: GRM1, GPRC1A, MGLU1, MGLUR1, PPP1R85, SCAR13

Reactivity: Rat

Host: Rabbit

Isotype: IgG

Gene ID: 2911

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human GRM1 (NP_001264993.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q13255

Santa Cruz:

Calculated MW: 101 kDa/132 kDa

Observed MW: 132 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

GRM1 Polyclonal Antibody DataSheet