GTPBP4 Polyclonal Antibody | G-AB-10504

GTPBP4 Polyclonal Antibody | G-AB-10504 | Gentaur Antibodies

Overview: GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: GTPBP4, CRFG, NGB, NOG1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 23560

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human GTPBP4 (NP_036473.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9BZE4

Santa Cruz:

Calculated MW: 60 kDa/68 kDa/73 kDa

Observed MW: 74 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:1000-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

GTPBP4 Polyclonal Antibody DataSheet