HDAC2 Polyclonal Antibody | G-AB-05895

HDAC2 Polyclonal Antibody | G-AB-05895 | Gentaur Antibodies

Overview: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Stem Cells

Synonyms: D10Wsu179e, HD 2, HD2, HDAC 2, Hdac2, HDAC2, Histone deacetylase 2 (HD2) , Histone deacetylase 2, OTTHUMP00000017046, OTTHUMP00000227077, OTTHUMP00000227078, RPD3, transcriptional regulator homolog RPD3, YAF1, YY1 associated factor 1, YY1 transcription factor binding protein, Yy1bp

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human HDAC2 around the non-phosphorylation site of Ser394.

Clone #:

Conjugation: Unconjugated

Swissprot: Q92769

Santa Cruz: sc-6296/sc-9959/sc-7899

Calculated MW: 55 kDa

Observed MW: 55 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification method: Affinity purification

Application: WB, IHC-p, ELISA

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

HDAC2 Polyclonal Antibody DataSheet