HIST1H2BA Polyclonal Antibody | G-AB-04900

HIST1H2BA Polyclonal Antibody | G-AB-04900 | Gentaur Antibodies

Overview: The nucleosome, made up of four core histone proteins (H2A, H2B, H3, and H4) , is the primary building block of chromatin. Originally thought to function as a static scaffold for DNA packaging, histones have now been shown to be dynamic proteins, undergoing multiple types of post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination, acetylation of specific lysine residues creates docking sites that facilitate recruitment of many transcription and chromatin regulatory proteins that contain a bromodomain, which binds to acetylated lysine residues . Histone H2B is rapidly phosphorylated at irradiation-induced DNA damage foci in mouse embryonic fibroblasts .

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: HIST1H2BA, testis, bA317E16.3, H2B, H2B histone family member U, H2B histone family member U testis specific, H2B histone family, member U, (testis specific) , H2B testis, H2B1A, H2BFU, H2BT, HIST1H2BA, Histone 1, H2ba, Histone cluster 1 H2ba, Histone H2B, Histone H2B testis, Histone H2B type 1 A, Histone H2B type 1-A, Histone H2B type 1A, STBP, Testis specific histone H2B, Testis-specific histone H2B, TSH 2B, TSH2B, TSH2B.1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP733759

Clonality: Polyclonal

Immunogen: Synthetic peptide of human HIST1H2BA

Clone #:

Conjugation: Unconjugated

Swissprot: Q96A08

Santa Cruz:

Calculated MW: 14 kDa

Observed MW: Refer to figures

Concentration: 1.98 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

HIST1H2BA Polyclonal Antibody DataSheet