HLA-E Polyclonal Antibody | G-AB-04405

HLA-E Polyclonal Antibody | G-AB-04405 | Gentaur Antibodies

Overview: HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin) . The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology

Synonyms: HLA class I histocompatibility antigen E alpha chain, EA1.2, EA2.1, HLA 6.2, HLA class I histocompatibility antigen alpha chain E, HLA class I histocompatibility antigen E alpha chain precursor, HLA class I histocompatibility antigen E alpha chain precursor, HLA6.2, HLAE, Lymphocyte antigen, Major histocompatibility complex class I E, MHC, MHC class I antigen E, MHC HLA E alpha 1, MHC HLA E alpha 2.1, QA1

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC002578

Clonality: Polyclonal

Immunogen: Fusion protein of human HLA-E

Clone #:

Conjugation: Unconjugated

Swissprot: P13747

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

HLA-E Polyclonal Antibody DataSheet