HORMAD2 Polyclonal Antibody | G-AB-06860
Gentaur Antibodies
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Gentaur Antibodies
HORMAD2 Polyclonal Antibody | G-AB-06860
- SKU:
- G-AB-06860
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
HORMAD2 Polyclonal Antibody | G-AB-06860 | Gentaur Antibodies
Overview: Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation (By similarity) .
Category Type: Polyclonal Antibody
Research Areas: Cell Biology
Synonyms: 4930529M09Rik, CT46.2, HORM2, HORMA domain containing 2, HORMA domain-containing protein 2, Hormad2, MGC26710, RP23-329P17.4
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: BC030013
Clonality: Polyclonal
Immunogen: Fusion protein of human HORMAD2
Clone #:
Conjugation: Unconjugated
Swissprot: Q8N7B1
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 0.96 mg/mL
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification method: Antigen affinity purification
Application: IHC, ELISA
Dilution: IHC 1:50-1:100, ELISA 1:5000-1:10000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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