HSD17B1 Polyclonal Antibody | G-AB-01721

HSD17B1 Polyclonal Antibody | G-AB-01721 | Gentaur Antibodies

Overview: Hydroxysteroid (17-beta) dehydrogenase 1 catalyzes the final step in the formation of estradiol and testosterone from estrone and androstenedione, respectively. Ovarian granulosa cells and breast tissue both express HSD17B1. Other tissues that express HSD17B1 include testis, placenta, uterus, prostate and adipose tissue. HSD17B1 functions as a homodimer and prefers NADP (H) over NAD (H) for oxidation and reduction. The gene encoding human HSD17B1 maps to chromosome 17q12-q21. The importance of HSD17B1 to estradiol production suggests the specific inhibition of HSD17B1 may aid in breast cancer therapy.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Neuroscience, Signal Transduction

Synonyms: 17 beta HSD 1, 17 beta hydroxysteroid dehydrogenase type 1, 17-beta-HSD 1, 17-beta-hydroxysteroid dehydrogenase type 1, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, DHB1, E17KSR, E2DH, EDH17B1, EDH17B2, EDHB17, Estradiol 17 beta dehydrogenase 1, Estradiol 17-beta-dehydrogenase 1, HSD17, HSD17B1, Hydroxysteroid (17 beta) dehydrogenase 1, MGC13814, Placental 17 beta hydroxysteroid dehydrogenase, Placental 17-beta-hydroxysteroid dehydrogenase, SDR28C1, Short chain dehydrogenase/reductase family 28CE, member 1

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_000404

Clonality: Polyclonal

Immunogen: Synthetic peptide of human HSD17B1

Clone #:

Conjugation: Unconjugated

Swissprot: P14061

Santa Cruz: sc-26964/sc-26963/sc-26965/sc-32872/sc-32871

Calculated MW: 35 kDa

Observed MW:

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

HSD17B1 Polyclonal Antibody DataSheet