HSD17B1 Polyclonal Antibody | G-AB-07451
Gentaur Antibodies
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Gentaur Antibodies
HSD17B1 Polyclonal Antibody | G-AB-07451
- SKU:
- G-AB-07451
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
HSD17B1 Polyclonal Antibody | G-AB-07451 | Gentaur Antibodies
Overview: Hydroxysteroid (17-beta) dehydrogenase 1 catalyzes the final step in the formation of estradiol and testosterone from estrone and androstenedione, respectively. Ovarian granulosa cells and breast tissue both express HSD17B1. Other tissues that express HSD17B1 include testis, placenta, uterus, prostate and adipose tissue. HSD17B1 functions as a homodimer and prefers NADP (H) over NAD (H) for oxidation and reduction. The gene encoding human HSD17B1 maps to chromosome 17q12-q21. The importance of HSD17B1 to estradiol production suggests the specific inhibition of HSD17B1 may aid in breast cancer therapy.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Metabolism, Neuroscience, Signal Transduction
Synonyms: HSD17B1, 17-beta-HSD, 20-alpha-HSD, E2DH, EDH17B2, EDHB17, HSD17, SDR28C1
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 3292
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human HSD17B1 (NP_000404.2) .
Clone #:
Conjugation: Unconjugated
Swissprot: P14061
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC, IF
Dilution: IHC 1:50-1:200 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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