IDH2 Polyclonal Antibody | G-AB-02556

IDH2 Polyclonal Antibody | G-AB-02556 | Gentaur Antibodies

Overview: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD (+) as the electron acceptor and the other NADP (+) . Five isocitrate dehydrogenases have been reported: three NAD (+) -dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP (+) -dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP (+) -dependent isozyme is a homodimer. The protein encoded by this gene is the NADP (+) -dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: D2HGA2, ICD-M, IDH, IDH2, IDHM, IDHP, IDP, IDPM, Isocitrate dehydrogenase [NADP], mitochondrial, Isocitrate dehydrogenase 2 (NADP+) , mitochondrial, mNADP-IDH, NADP (+) -specific ICDH, Oxalosuccinate decarboxylase

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC009244

Clonality: Polyclonal

Immunogen: Recombinant protein of human IDH2

Clone #:

Conjugation: Unconjugated

Swissprot: P48735

Santa Cruz: sc-55664/sc-55666/sc-55668/sc-134923

Calculated MW: 51 kDa

Observed MW:

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:100-1:300

Storage: Store at -20°C. Avoid freeze / thaw cycles.

IDH2 Polyclonal Antibody DataSheet