IL10RA Polyclonal Antibody | G-AB-09774

IL10RA Polyclonal Antibody | G-AB-09774 | Gentaur Antibodies

Overview: The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology

Synonyms: IL10RA, CD210, CD210a, CDW210A, HIL-10R, IL-10R1, IL10R

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 3587

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human IL10RA (NP_001549.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q13651

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

IL10RA Polyclonal Antibody DataSheet