IL12RB1 Polyclonal Antibody | G-AB-08158
Gentaur Antibodies
- SKU:
- G-AB-08158
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Rat
IL12RB1 Polyclonal Antibody | G-AB-08158 | Gentaur Antibodies
Overview: The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants.
Category Type: Polyclonal Antibody
Research Areas: Immunology
Synonyms: IL12RB1, CD212, IL-12R-BETA1, IL12RB, IMD30
Reactivity: Human, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 3594
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human IL12RB1 (NP_714912.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: P42701
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC, IF
Dilution: IHC 1:50-1:200 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.