IL18BP Polyclonal Antibody | G-AB-11103

IL18BP Polyclonal Antibody | G-AB-11103 | Gentaur Antibodies

Overview: The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology

Synonyms: IL18BP, IL18BPa

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 10068

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human IL18BP (NP_001138529.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O95998

Santa Cruz:

Calculated MW: 12 kDa/17 kDa/21 kDa

Observed MW: 38 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

IL18BP Polyclonal Antibody DataSheet