IL1B Polyclonal Antibody | G-AB-06084

IL1B Polyclonal Antibody | G-AB-06084 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE) . This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Immunology

Synonyms: Catabolin, H1, IL 1, IL 1 beta, IL-1 beta, IL1 BETA, IL1B, IL1B, IL1F2, Interleukin 1 beta, Interleukin-1 beta, OAF, OTTHUMP00000162031, Preinterleukin 1 beta, Pro interleukin 1 beta

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC008678

Clonality: Polyclonal

Immunogen: Fusion protein of human IL1B

Clone #:

Conjugation: Unconjugated

Swissprot: P01584

Santa Cruz:

Calculated MW: 31 kDa

Observed MW: Refer to figures

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, ELISA

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

IL1B Polyclonal Antibody DataSheet