ILF3 Polyclonal Antibody | G-AB-10081
Gentaur Antibodies
Write a Review
Gentaur Antibodies
ILF3 Polyclonal Antibody | G-AB-10081
- SKU:
- G-AB-10081
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
ILF3 Polyclonal Antibody | G-AB-10081 | Gentaur Antibodies
Overview: This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction
Synonyms: ILF3, CBTF, DRBF, DRBP76, MMP4, MPHOSPH4, MPP4, NF-AT-90, NF110, NF110b, NF90, NF90a, NF90b, NFAR, NFAR-1, NFAR2, TCP110, TCP80
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 3609
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human ILF3 (NP_036350.2) .
Clone #:
Conjugation: Unconjugated
Swissprot: Q12906
Santa Cruz:
Calculated MW: 74 kDa/75 kDa/76 kDa/82 kDa/95 kDa
Observed MW: 95 kDa/120 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IF
Dilution: WB 1:500-1:2000 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Related Products
