IPO4 Polyclonal Antibody | G-AB-01067

IPO4 Polyclonal Antibody | G-AB-01067 | Gentaur Antibodies

Overview: Importin-4is aproteinthat in humans is encoded by theIPO4gene. Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms: Imp4, Imp4b, Importin 4, Importin 4b, Importin-4, Importin-4b, Ipo4, IPO4, Ran binding protein 4, Ran-binding protein 4, RanBP4

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC003690

Clonality: Polyclonal

Immunogen: Recombinant protein of human IPO4

Clone #:

Conjugation: Unconjugated

Swissprot: Q8TEX9

Santa Cruz: sc-55280/sc-55283/sc-292402

Calculated MW: 119 kDa

Observed MW:

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

IPO4 Polyclonal Antibody DataSheet