ISCU Polyclonal Antibody | G-AB-10502

ISCU Polyclonal Antibody | G-AB-10502 | Gentaur Antibodies

Overview: This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1.

Category Type: Polyclonal Antibody

Research Areas: Metabolism, Signal Transduction

Synonyms: ISCU, 2310020H20Rik, HML, ISU2, NIFU, NIFUN, hnifU

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 23479

Accession #:

Clonality:

Immunogen: A synthetic Peptide of human ISCU

Clone #:

Conjugation: Unconjugated

Swissprot: Q9H1K1

Santa Cruz:

Calculated MW: 15 kDa/17 kDa

Observed MW: 26 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:1000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ISCU Polyclonal Antibody DataSheet