ITCH Polyclonal Antibody | G-AB-09108

ITCH Polyclonal Antibody | G-AB-09108 | Gentaur Antibodies

Overview: This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cell Biology

Synonyms: ITCH, ADMFD, AIF4, AIP4, NAPP1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 83737

Accession #:

Clonality:

Immunogen: A synthetic peptide of human ITCH (NP_001244066.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q96J02

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ITCH Polyclonal Antibody DataSheet