KCNQ1 Polyclonal Antibody | G-AB-02578

KCNQ1 Polyclonal Antibody | G-AB-02578 | Gentaur Antibodies

Overview: This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome) , Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS) , and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction

Synonyms: ATFB1, ATFB3, FLJ26167, IKs producing slow voltage-gated potassium channel subunit alpha, IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1, Jervell and Lange-Nielsen syndrome 1, JLNS1, KCNA8, KCNA9, KCNQ1, KCNQ1, kidney and cardiac voltage dependend K+ channel, KQT-like 1, Kv1.9, Kv7.1, KVLQT1, long (electrocardiographic) QT syndrome, Ward-Romano syndrome 1, LQT, LQT1, Potassium channel, voltage-gated, shaker-relatd subfamily, member 9, Potassium voltage-gated channel subfamily KQT member 1, potassium voltage-gated channel, KQT-like subfamily, member 1, RWS, slow delayed rectifier channel subunit, SQT2, Voltage-gated potassium channel subunit Kv7.1, WRS

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_000209

Clonality: Polyclonal

Immunogen: Recombinant protein of human KCNQ1

Clone #:

Conjugation: Unconjugated

Swissprot: P51787

Santa Cruz: sc-10645/sc-10646/sc-20816

Calculated MW: 75 kDa

Observed MW:

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:200-1:1000, IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

KCNQ1 Polyclonal Antibody DataSheet