KEAP1 Polyclonal Antibody | G-AB-04700

KEAP1 Polyclonal Antibody | G-AB-04700 | Gentaur Antibodies

Overview: KEAP1, also named as INRF2, KIAA0132 and KLHL19, is part of a multiprotein complex that contains the CUL3-ROC1 ubiquitin ligase, which can ubiquitinate the N-terminal domain of NRF2. Two molecules of KEAP1 bind to two distinct sites in the N-terminal region of NRF2, the ETGE and DLG sites, which affect the KEAP1-NRF2 interaction and/or its physiological consequences. KEAP1 retains NFE2L2/NRF2 in the cytosol. It functions as substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1. It also retains BPTF in the cytosol. This antibody is a mouse monoclonal antibody raised against residues near the C terminus of human KEAP1.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: Cytosolic inhibitor of Nrf2, INrf 2, INrf2, Keap 1, KEAP1, KEAP1, Kelch like ECH associated protein 1, Kelch like family member 19, Kelch like protein 19, Kelch-like ECH-associated protein 1, Kelch-like protein 19, KIAA0132, KLHL 19, KLHL19, MGC10630, MGC1114, MGC20887, MGC4407, MGC9454

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP036421

Clonality: Polyclonal

Immunogen: Synthetic peptide of human KEAP1

Clone #:

Conjugation: Unconjugated

Swissprot: Q14145

Santa Cruz:

Calculated MW: 70 kDa

Observed MW: Refer to figures

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

KEAP1 Polyclonal Antibody DataSheet