KLF1 Polyclonal Antibody | G-AB-04905

KLF1 Polyclonal Antibody | G-AB-04905 | Gentaur Antibodies

Overview: This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In (Lu) blood phenotype.KLF1 (Kruppel Like Factor 1) is a Protein Coding gene. Diseases associated with KLF1 include Dyserythropoietic Anemia, Congenital, Type Iv and Hereditary Persistence Of Fetal Hemoglobin-Sickle Cell Disease Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is KLF4.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: CDAN4, EKLF, EKLF PEN, Erythroid krueppel like transcription factor (EKLF) (Erythroid transcription factor) , Erythroid krueppel-like transcription factor, Erythroid Kruppel like factor, Erythroid specific transcription factor EKLF, HBFQTL6, Human erythroid-specific transcription factor EKLF mRNA complete cds, INLU, Klf1, KLF1, Krueppel-like factor 1, Kruppel like factor 1 (erythroid)

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP006554

Clonality: Polyclonal

Immunogen: Synthetic peptide of human KLF1

Clone #:

Conjugation: Unconjugated

Swissprot: Q13351

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.96 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:100, ELISA 1:2000-1:5000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

KLF1 Polyclonal Antibody DataSheet