KLF4 Polyclonal Antibody | G-AB-11225

KLF4 Polyclonal Antibody | G-AB-11225 | Gentaur Antibodies

Overview: This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Developmental Biology, Stem Cells

Synonyms: EZF, GKLF, KLF4

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 9314

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human KLF4 (NP_004226.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: O43474

Santa Cruz:

Calculated MW: 6 kDa/12 kDa/45 kDa/51 kDa/54 kDa

Observed MW: 50 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

KLF4 Polyclonal Antibody DataSheet