KRIT1 Polyclonal Antibody | G-AB-11354
Gentaur Antibodies
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Gentaur Antibodies
KRIT1 Polyclonal Antibody | G-AB-11354
- SKU:
- G-AB-11354
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
KRIT1 Polyclonal Antibody | G-AB-11354 | Gentaur Antibodies
Overview: This gene encodes a protein containing four ankyrin repeats, a band 4.1/ezrin/radixin/moesin (FERM) domain, and multiple NPXY sequences. The encoded protein is localized in the nucleus and cytoplasm. It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha) , and plays a critical role in beta1-integrin-mediated cell proliferation. It associates with junction proteins and RAS-related protein 1A (Rap1A) , which requires the encoded protein for maintaining the integrity of endothelial junctions. It is also a microtubule-associated protein and may play a role in microtubule targeting. Mutations in this gene result in cerebral cavernous malformations. Multiple alternatively spliced transcript variants have been found for this gene.
Category Type: Polyclonal Antibody
Research Areas:
Synonyms: KRIT1, CAM, CCM1
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 889
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human KRIT1 (NP_919438.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: O00522
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IF
Dilution: IF 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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