KRTAP11-1 Polyclonal Antibody | G-AB-07020

KRTAP11-1 Polyclonal Antibody | G-AB-07020 | Gentaur Antibodies

Overview: Hair is a structure that is unique to mammals. It plays an important role in the retention of heat, as well as sexual dimorphism, attraction of mates and protection of skin. The major components of hair are -keratins and keratin-associated proteins (KRTAPs or KAPs) , each of which are encoded by multigene families. Hair keratins form an intermediate filament (IF) network, which is embedded in an interfilamentous matrix consisting of KRTAPs. KRTAPS comprise three major groups, which are essential for the formation of rigid and resistant hair shafts through disulfide bond cross-linking or hydrophobic interactions with keratins. These groups are designated high cysteine (HS) , which includes subfamilies 1, 2, 3, 10, 12, 16, 29 and 31, ultrahigh cysteine, including subfamilies 4, 5, 9, 17, 28, 30, 32 and 33, and high glycine-tyrosine (HGT) , which includes subfamilies 6, 7, 8, 19, 20 and 21. In addition, subfamilies 11, 13, 24-27, 29, 34 and 35 have high serine content but relative low cysteine content. After further phylogenetic studies, subfamilies 14 and 15 have been grouped with subfamily 13 and subfamily 22 was combined with subfamily 19.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: HACL 1, HACL1, High sulfur keratin-associated protein 11.1, High sulphur keratin-associated protein 11.1, KAP11.1, keratin associated protein 11-1, KRTAP11 1

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP787054

Clonality: Polyclonal

Immunogen: Synthetic peptide of human KRTAP11-1

Clone #:

Conjugation: Unconjugated

Swissprot: Q8IUC1

Santa Cruz:

Calculated MW: 17 kDa

Observed MW: Refer to figures

Concentration: 1.1 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, ELISA

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

KRTAP11-1 Polyclonal Antibody DataSheet