LEPR Polyclonal Antibody | G-AB-06942
Gentaur Antibodies
- SKU:
- G-AB-06942
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
LEPR Polyclonal Antibody | G-AB-06942 | Gentaur Antibodies
Overview: The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight) , and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021) .
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction
Synonyms: CD 295, CD295, CD295 antigen, Db, Fa, HuB219, LEP R, LEP-R, LEPR, LEPR, LEPRD, Leptin receptor, Leptin receptor fatty, Leptin receptor gene related protein, Leptin receptor precursor, Leptin receptor precursor, OB R gene related protein, OB receptor, OB-R, OB-RGRP, obl, Obr
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: NP002294
Clonality: Polyclonal
Immunogen: Synthetic peptide of human LEPR
Clone #:
Conjugation: Unconjugated
Swissprot: P48357
Santa Cruz:
Calculated MW: 133 kDa
Observed MW: Refer to figures
Concentration: 0.84 mg/mL
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification method: Antigen affinity purification
Application: WB, IHC, ELISA
Dilution: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
Storage: Store at -20°C. Avoid freeze / thaw cycles.