LMNB1 Polyclonal Antibody | G-AB-03914

LMNB1 Polyclonal Antibody | G-AB-03914 | Gentaur Antibodies

Overview: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD) .

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Signal Transduction, Tags & Cell Markers

Synonyms: ADLD, lamin B1, Lamin-B1, LMN, LMN2, LMNB, Lmnb1, LMNB1, MGC111419, OTTHUMP00000159218

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC012295

Clonality: Polyclonal

Immunogen: Fusion protein of human LMNB1

Clone #:

Conjugation: Unconjugated

Swissprot: P20700

Santa Cruz:

Calculated MW: 67 kDa

Observed MW: Refer to figures

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:1000-1:5000, IHC 1:100-1:300, ELISA 1:2000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

LMNB1 Polyclonal Antibody DataSheet