LPIN1 Polyclonal Antibody | G-AB-03644

LPIN1 Polyclonal Antibody | G-AB-03644 | Gentaur Antibodies

Overview: This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM) . This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction

Synonyms: EC=3.1.3.4, KIAA0188, Lipin-1, Lpin1, LPIN1, PAP1, Phosphatidate phosphatase LPIN1

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP663731

Clonality: Polyclonal

Immunogen: Synthetic peptide of human LPIN1

Clone #:

Conjugation: Unconjugated

Swissprot: Q14693

Santa Cruz:

Calculated MW: 99 kDa

Observed MW: Refer to figures

Concentration: 1.4 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

LPIN1 Polyclonal Antibody DataSheet