LRP6 Polyclonal Antibody | G-AB-03470

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$163.00 - $465.00
SKU:
G-AB-03470
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse
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LRP6 Polyclonal Antibody | G-AB-03470 | Gentaur Antibodies

Overview: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction, Stem cells

Synonyms: ADCAD2, C030016K15Rik, Cd, FLJ90062, FLJ90421, LDL receptor related protein 6, Low density lipoprotein receptor related protein 6, Low-density lipoprotein receptor-related protein 6, LRP-6, LRP6, LRP6, OTTHUMP00000238979, OTTHUMP00000238980, OTTHUMP00000238982, STHAG7

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC143725

Clonality: Polyclonal

Immunogen: Synthetic peptide of human LRP6

Clone #:

Conjugation: Unconjugated

Swissprot: O75581

Santa Cruz: sc-17982/sc-17984/sc-134462/sc-15399

Calculated MW:

Observed MW:

Concentration: 1.4 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:40-200, ELISA 1:2000-10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

LRP6 Polyclonal Antibody DataSheet

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