MAFA Polyclonal Antibody | G-AB-07009

MAFA Polyclonal Antibody | G-AB-07009 | Gentaur Antibodies

Overview: Members of the Maf family of basic region/leucine zipper (bZIP) transcription factors affect transcription in either a positive or negative fashion, depending on their particular protein partner and the context of the target promoter. c-Maf (Maf-2) and the closely related family members.MAFA acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms: HMafA, Mafa, MAFA, Pancreatic beta cell specific transcriptional activator, Pancreatic beta-cell-specific transcriptional activator, RIPE3b1, Transcription factor MafA, Transcription factor RIPE3b1, v maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) , v maf musculoaponeurotic fibrosarcoma oncogene homolog A, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP963883

Clonality: Polyclonal

Immunogen: Synthetic peptide of human MAFA

Clone #:

Conjugation: Unconjugated

Swissprot: Q8NHW3

Santa Cruz:

Calculated MW: 37 kDa

Observed MW: Refer to figures

Concentration: 1.2 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, ELISA

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MAFA Polyclonal Antibody DataSheet